The GRACE score was validated in various databases and c-statistics of the GRACE score was estimated to be 0.83 in the original database. It has been observed that the odds of in-hospital mortality have increased significantly with increase in GRACE score. GRACE score is one of the score that was developed to identify patients in the coronary care unit or emergency department at the greatest risk of adverse events after ACS. There are many risk scores for ACS risk stratification. Currently, there is actually no evidence based risk stratification and guidelines for these patients. A huge number of patients with chest pain due to factors other than ACS were not assessed in these studies. But none of the scoring systems were used to identify the ACS in the emergency room. The risk scores such as the thrombolysis in myocardial infarction (TIMI), platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin (PURSUIT), fast revascularization in instability in coronary disease (FRISC), and Global Registry of Acute Coronary Events (GRACE) are well validated in this regard. For patients with confirmed ACS diagnosis, various scoring systems may be used in order to differentiate patients in the coronary care unit that benefit more from the treatments. Īccurate stratification of risk factors and diagnostic evaluation are of the highest significance not just for primary prevention but even for the prevention of repeated coronary ischemia or infarction attacks. Life-saving therapies for ACS patients are strongly dependent on early and prompt identification of signs and symptoms, whereas atypical appearance of ACS symptoms may lead to delayed diagnosis, delayed care, less evidence-based approaches, and increased morbidity and mortality. The clinical characteristics of ACS, including ST segment elevation of myocardial infarction (STEMI), non-STEMI, and unstable angina, is known to be widespread causes for disability and mortality. GRACE risk score has good predictive value for the prediction of in-hospital mortality and 6 months mortality among patients with NSTE-ACS.Īcute coronary syndrome (ACS) is a syndrome caused by decreased blood flow in the coronary arteries. After adjustment, diabetes mellitus, family history, and GRACE score remained significantly associated with in-hospital mortality ( p ≤ 0.05) and age remained significantly associated with 6 months mortality. In univariate analysis, gender, diabetes mellitus, family history, smoking, and GRACE score were significantly associated with in-hospital mortality whereas age, obesity, dyslipidemia, and GRACE were significantly associated with 6 months mortality. ![]() In high risk category, 10.5% of the patients died within hospital stay and 11.8% died within 6 months ( p = 0.001 and p = 0.013). Of 284 patients at 6 months assessment, 10 patients died (3.5%), 240 survived (84.5%), and 34 were lost to follow-up (12%) respectively. In this observational study, 300 patients with NSTE-ACS of age more than 30 years were included 16 patients died during the hospital stay (5.3%). ![]() The aim of this study was to determine the predictive value of the Global Registry of Acute Coronary Events (GRACE) score for predicting in-hospital and 6 months mortality after non-ST elevation acute coronary syndrome (NSTE-ACS).
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